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Company Analysis

KPTI Insider Trading

Karyopharm Therapeutics Inc. | Pharmaceutical Preparations

Comprehensive Trading Performance Summary

The investment history of corporate insiders at Karyopharm Therapeutics Inc. provides a unique lens into the internal conviction of the company's leadership. By analyzing SEC Form 4 filings, investors can track how directors and officers are allocating their own capital. High-conviction buying often signals that management believes the current market price significantly undervalues future growth prospects, while strategic selling might occur for personal liquidity or portfolio diversification. Monitoring these shifts in ownership is essential for understanding the alignment between management and shareholders in the Pharmaceutical Preparations sector.

Transactions on Chart

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Filing Date Trade Date Reporting Person Relationship Type Price Qty Total, $ Owned After Change, %
2022-05-05 23:08 2022-05-04 Paulson Richard A. Director, Officer - President and CEO SELL $6.23 28,502 $177,510 633,448 -4.3%
2022-03-02 23:34 2022-02-28 Frenkel Ran Officer - EVP, Chief Dev. Officer SELL $10.24 1,663 $17,025 168,290 -1.0%
2022-03-02 23:33 2022-02-28 Mason Michael Officer - EVP, CFO & Treasurer SELL $10.24 2,398 $24,550 139,110 -1.7%
2022-03-02 23:20 2022-02-28 Shacham Sharon Officer - Chief Scientific Officer SELL $10.24 12,452 $127,477 713,757 -1.7%
2022-03-02 23:18 2022-02-28 Kauffman Michael Director SELL $10.24 12,452 $127,477 898,131 -1.4%
2022-02-23 00:19 2022-02-17 Shah Jatin Officer - EVP, Chief Medical Officer SELL $12.12 1,306 $15,833 129,450 -1.0%
2022-02-23 00:16 2022-02-17 Frenkel Ran Officer - EVP, Chief Dev. Officer SELL $12.12 2,929 $35,509 101,703 -2.8%
2022-02-23 00:15 2022-02-17 Shacham Sharon Officer - Chief Scientific Officer SELL $12.12 18,167 $220,246 698,983 -2.5%
2022-02-23 00:14 2022-02-17 Kauffman Michael Director SELL $12.12 18,167 $220,246 904,357 -2.0%
2022-02-10 01:27 2022-02-07 Shah Jatin Officer - EVP, Chief Medical Officer SELL $9.86 1,704 $16,805 130,756 -1.3%
2022-02-10 01:26 2022-02-07 Frenkel Ran Officer - EVP, Chief Dev. Officer SELL $9.86 1,991 $19,635 104,632 -1.9%
2022-02-10 01:25 2022-02-07 Mason Michael Officer - EVP, CFO & Treasurer SELL $9.86 3,947 $38,925 53,308 -6.9%
2022-02-10 01:22 2022-02-07 Shacham Sharon Officer - Chief Scientific Officer SELL $9.86 13,471 $132,851 708,062 -1.9%
2022-02-10 01:24 2022-02-07 Kauffman Michael Director SELL $9.86 13,471 $132,851 913,445 -1.5%
2021-12-04 02:17 2021-12-02 Mitchener Stephen Officer - SVP, Chief Business Officer SELL $6.69 499 $3,338 3,296 -13.1%
2021-06-03 23:06 2021-06-02 Mitchener Stephen Officer - SVP, Chief Business Officer SELL $9.29 528 $4,905 2,472 -17.6%
2021-05-11 15:58 2021-05-07 Shah Jatin Officer - EVP, Chief Medical Officer BUY $8.60 23,250 $199,992 131,802 +21.4%
2021-05-11 02:57 2021-05-06 BOHLIN GAREN G Director BUY $7.82 4,000 $31,280 4,000 +100.0%
2021-03-23 14:50 2021-03-18 Shacham Sharon Officer - President & CSO SELL $12.39 4,000 $49,553 714,826 -0.6%
2021-03-23 14:48 2021-03-18 Kauffman Michael Director, Officer - Chief Executive Officer SELL $12.39 4,000 $49,553 714,826 -0.6%
2021-02-23 04:12 2021-02-18 Shah Jatin Officer - EVP, Chief Medical Officer SELL $14.83 1,186 $17,590 51,791 -2.2%
2021-02-23 04:11 2021-02-18 Frenkel Ran Officer - EVP, Chief Dev. Officer SELL $14.83 2,887 $42,818 46,126 -5.9%
2021-02-23 04:10 2021-02-18 Shacham Sharon Officer - President & CSO SELL $14.83 18,990 $281,644 575,126 -3.2%
2021-02-23 04:09 2021-02-18 Kauffman Michael Director, Officer - Chief Executive Officer SELL $14.83 18,990 $281,644 776,452 -2.4%
2021-02-18 02:48 2021-02-11 Shah Jatin Officer - EVP, Chief Medical Officer OPT+S $15.52 1,748 $27,127 48,127 0.0%
2021-02-18 02:47 2021-02-11 Frenkel Ran Officer - EVP, Chief Dev. Officer OPT+S $15.52 2,046 $31,752 39,338 0.0%
2021-02-18 02:46 2021-02-11 Mason Michael Officer - SVP, CFO & Treasurer SELL $15.52 2,858 $44,354 5,292 -35.1%
2021-02-18 02:45 2021-02-11 Shacham Sharon Officer - President & CSO OPT+S $15.52 13,243 $205,518 562,821 0.0%
2021-02-18 02:49 2021-02-11 Lewis Tanya Officer - EVP, Chief Reg. Affairs SELL $15.52 2,046 $31,752 4,143 -33.1%
2021-02-18 02:44 2021-02-11 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $15.52 13,243 $205,518 764,147 0.0%
2020-12-23 02:16 2020-12-18 Mirza Mansoor Raza Director OPT+S $18.00 5,000 $90,000 0 0.0%
2020-12-09 01:14 2020-12-07 Mirza Mansoor Raza Director OPT+S $16.07 20,000 $321,384 0 0.0%
2020-12-04 01:17 2020-12-01 Primiano Christopher Brett Officer - EVP, CBO, GC & Secretary OPT+S $17.53 137,061 $2,402,227 4,523 0.0%
2020-11-05 04:16 2020-07-15 Shah Jatin Officer - EVP, Chief Medical Officer OPT+S $19.46 589 $11,462 43,229 0.0%
2020-11-05 00:09 2020-11-02 Primiano Christopher Brett Officer - EVP, CBO, GC & Secretary SELL $14.92 772 $11,518 4,523 -14.6%
2020-11-05 04:18 2020-10-30 Lewis Tanya Officer - EVP,Chief Reg.&Quality Officer OPT+S $15.58 226 $3,521 539 0.0%
2020-10-15 01:00 2020-10-13 Primiano Christopher Brett Officer - EVP, CBO, GC & Secretary OPT+S $16.86 39,271 $661,968 4,649 0.0%
2020-10-15 00:54 2020-10-12 Shacham Sharon Officer - President & CSO OPT+S $14.89 7,500 $111,683 756,489 0.0%
2020-10-15 00:56 2020-10-12 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $14.89 7,500 $111,683 756,489 0.0%
2020-09-10 15:49 2020-09-08 Primiano Christopher Brett Officer - EVP, CBO, GC & Secretary OPT+S $14.98 10,054 $150,609 4,649 0.0%
2020-08-27 23:00 2020-08-26 DEMAREE JOHN Officer - Chief Commercial Officer BUY $14.54 7,500 $109,013 7,500 +100.0%
2020-08-19 01:05 2020-08-17 Shacham Sharon Officer - President & CSO OPT+S $15.00 1,477 $22,155 756,489 0.0%
2020-08-19 01:07 2020-08-17 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $15.00 1,477 $22,155 756,489 0.0%
2020-07-17 23:24 2020-07-15 Shacham Sharon Officer - President & CSO OPT+S $19.43 7,500 $145,723 756,489 0.0%
2020-07-17 23:26 2020-07-15 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $19.43 7,500 $145,723 756,489 0.0%
2020-07-14 01:43 2020-07-09 Shacham Sharon Officer - President & CSO OPT+S $19.27 15,000 $289,026 555,122 0.0%
2020-07-14 01:45 2020-07-09 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $19.27 15,000 $289,026 756,489 0.0%
2020-06-24 23:05 2020-06-22 Shacham Sharon Officer - President & CSO OPT+S $20.00 7,500 $150,000 756,489 0.0%
2020-06-24 23:07 2020-06-22 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $20.00 7,500 $150,000 756,489 0.0%
2020-06-17 23:05 2020-06-15 Shacham Sharon Officer - President & CSO OPT+S $16.37 7,500 $122,780 756,489 0.0%
SHOW ENTRIES

How to Interpret $KPTI Trades

Not every insider transaction in Karyopharm Therapeutics Inc. is a signal for immediate action. Professional investors look for "cluster buying"—when multiple executives simultaneously purchase $KPTI shares on the open market. It is crucial to distinguish between scheduled sales (under Rule 10b5-1) and voluntary increases in ownership, which demonstrate management’s true conviction that the stock is undervalued.

Data Source & Accuracy for KPTI

Insider activity data for Karyopharm Therapeutics Inc. is streamed in real-time directly from the SEC EDGAR system. We analyze raw Form 4 filings, filtering out technical adjustments and complex derivative transactions. This provides a transparent view of how ownership structure is evolving in $KPTI, allowing you to follow the capital of those with the most intimate knowledge of the company.

UNDERSTANDING THE DATA

FILING DATE: The date and time when the transaction was reported to the SEC. This is when the public first receives the information.

TRADE DATE: The actual day the insider executed the purchase or sale in the market.

INDUSTRY: The specific market sector the company operates in. Useful for identifying broader institutional capital flows across sectors.

OWNED AFTER: The total number of shares held by the insider following the transaction. This highlights the insider's remaining conviction in the company.

CHANGE %: The percentage increase or decrease of the insider's total position. Large percentage changes often carry more weight than the dollar amount alone.

TRADE TYPES DEFINITIONS

BUY: An open market purchase. Typically indicates an insider's belief that the stock is undervalued or poised for growth.

SELL: An open market sale. While often used for diversification or liquidity, large or unexpected sales can be a warning signal.

OPT+S (OPTION EXERCISE & SALE): This occurs when an insider exercises their stock options and sells them immediately. Often part of a structured compensation plan.