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Company Analysis

KPTI Insider Trading

Karyopharm Therapeutics Inc. | Pharmaceutical Preparations

Comprehensive Trading Performance Summary

The investment history of corporate insiders at Karyopharm Therapeutics Inc. provides a unique lens into the internal conviction of the company's leadership. By analyzing SEC Form 4 filings, investors can track how directors and officers are allocating their own capital. High-conviction buying often signals that management believes the current market price significantly undervalues future growth prospects, while strategic selling might occur for personal liquidity or portfolio diversification. Monitoring these shifts in ownership is essential for understanding the alignment between management and shareholders in the Pharmaceutical Preparations sector.

Transactions on Chart

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Filing Date Trade Date Reporting Person Relationship Type Price Qty Total, $ Owned After Change, %
2018-02-21 00:21 2018-02-15 Primiano Christopher Brett Officer - EVP, CBO, GC & Secretary SELL $15.01 2,500 $37,527 7,381 -25.3%
2018-02-13 00:32 2018-02-08 Mirza Mansoor Raza Director OPT+S $14.00 1,500 $21,000 0 0.0%
2018-02-09 00:11 2018-02-07 Mirza Mansoor Raza Director OPT+S $13.00 1,500 $19,500 0 0.0%
2018-02-09 00:10 2018-02-07 Primiano Christopher Brett Officer - EVP, CBO, GC & Secretary SELL $13.00 1,500 $19,500 9,881 -13.2%
2018-02-09 00:07 2018-02-07 Shacham Sharon Officer - President & CSO OPT+S $12.50 10,000 $125,048 713,510 0.0%
2018-02-09 00:08 2018-02-07 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $12.50 10,000 $125,048 713,510 0.0%
2018-01-23 00:08 2018-01-18 Shacham Sharon Officer - President & CSO OPT+S $10.09 10,000 $100,882 512,143 0.0%
2018-01-23 00:05 2018-01-18 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $10.09 10,000 $100,882 512,143 0.0%
2018-01-10 00:08 2018-01-08 Shacham Sharon Officer - President & CSO OPT+S $10.08 10,000 $100,769 713,510 0.0%
2018-01-10 00:10 2018-01-08 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $10.08 10,000 $100,769 713,510 0.0%
2017-12-21 00:21 2017-12-18 Shacham Sharon Officer - President & CSO OPT+S $9.16 10,000 $91,553 512,143 0.0%
2017-12-21 00:19 2017-12-18 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $9.16 10,000 $91,553 512,143 0.0%
2017-12-14 00:04 2017-12-11 Primiano Christopher Brett Officer - SVP, OPS, BUS DEV, GC & SEC OPT+S $10.28 27,042 $277,873 11,381 0.0%
2017-12-09 00:05 2017-12-07 Shacham Sharon Officer - President & CSO OPT+S $10.39 10,000 $103,903 713,510 0.0%
2017-12-09 00:07 2017-12-07 Kauffman Michael Director, Officer - Chief Executive Officer OPT+S $10.39 10,000 $103,903 713,510 0.0%
2017-11-10 00:04 2017-11-07 Frenkel Ran Officer - Chief Dev Operations Officer SELL $11.25 4,958 $55,755 24,733 -16.7%
2017-11-10 00:03 2017-11-07 Primiano Christopher Brett Officer - SVP, OPS, BUS DEV, GC & SEC SELL $11.25 4,958 $55,755 21,423 -18.8%
2017-10-04 23:08 2017-10-02 Mirza Mansoor Raza Director OPT+S $12.00 2,000 $24,000 0 0.0%
2017-10-04 23:06 2017-10-02 Primiano Christopher Brett Officer - SVP, OPS, BUS DEV, GC & SEC SELL $12.00 1,500 $18,000 11,381 -11.6%
2017-09-18 23:11 2017-09-15 Mirza Mansoor Raza Director OPT+S $11.00 2,882 $31,702 0 0.0%
2017-09-18 23:09 2017-09-15 Primiano Christopher Brett Officer - SVP, OPS, BUS DEV, GC & SEC SELL $11.00 2,000 $22,000 12,881 -13.4%
2017-09-13 23:13 2017-09-11 Mirza Mansoor Raza Director OPT+S $11.00 118 $1,298 0 0.0%
2017-09-02 00:43 2017-06-26 Primiano Christopher Brett Officer - SVP, OPS, BUS DEV, GC & SEC SELL $10.03 805 $8,071 14,881 -5.1%
2017-08-30 23:09 2017-08-29 Primiano Christopher Brett Officer - SVP, OPS, BUS DEV, GC & SEC SELL $10.00 2,195 $21,950 15,686 -12.3%
2016-11-16 00:05 2016-11-14 Frenkel Ran Officer - Chief Dev Operations Officer SELL $10.06 3,309 $33,286 14,691 -18.4%
2016-11-15 01:48 2016-11-09 Primiano Christopher Brett Officer - SVP,CORP DEV,GEN COUNSEL&SEC. SELL $8.19 4,342 $35,544 15,819 -21.5%
2016-11-15 01:49 2016-11-09 Renz Justin A Officer - EVP, CFO & Treasurer SELL $8.19 4,342 $35,544 19,173 -18.5%
2016-06-28 01:44 2016-06-23 Chione Ltd 10% owner SELL $8.03 18,824 $151,083 8,549,920 -0.2%
2016-06-15 21:56 2016-06-13 Chione Ltd 10% owner SELL $8.51 7,074 $60,214 8,568,744 -0.1%
2016-06-10 22:20 2016-06-08 Chione Ltd 10% owner SELL $9.21 45,541 $419,282 8,575,818 -0.5%
2016-06-08 23:51 2016-06-06 Chione Ltd 10% owner SELL $9.24 40,000 $369,552 8,621,359 -0.5%
2016-06-07 03:55 2016-06-02 Chione Ltd 10% owner SELL $9.65 17,855 $172,244 8,661,359 -0.2%
2016-06-02 03:04 2016-05-27 Chione Ltd 10% owner SELL $9.61 74,664 $717,603 8,679,214 -0.9%
2016-05-28 01:27 2016-05-25 Chione Ltd 10% owner SELL $9.73 46,122 $448,827 8,753,878 -0.5%
2016-05-24 03:16 2016-05-19 Chione Ltd 10% owner SELL $8.54 93,932 $801,804 8,800,000 -1.1%
2016-05-20 03:54 2016-05-17 Chione Ltd 10% owner SELL $8.15 63,800 $519,970 8,893,932 -0.7%
2016-05-18 04:11 2016-05-13 Chione Ltd 10% owner SELL $8.01 10,400 $83,269 8,957,732 -0.1%
2016-05-13 02:52 2016-05-10 Chione Ltd 10% owner SELL $8.24 31,868 $262,646 8,968,132 -0.4%
2015-12-11 00:12 2015-12-08 Mirza Mansoor Raza Director OPT+S $15.01 15,000 $225,137 0 0.0%
2015-04-08 23:12 2015-04-06 Frenkel Ran Officer - EVP, WW Development Operations BUY $31.81 3,000 $95,430 3,000 +100.0%
2015-04-07 00:53 2015-04-02 Renz Justin A Officer - EVP, CFO & Treasurer BUY $29.71 5,000 $148,557 5,000 +100.0%
2015-04-07 00:57 2015-04-02 Greene Barry E Director BUY $29.31 3,000 $87,938 3,000 +100.0%
2015-01-15 00:07 2015-01-12 Shacham Sharon Officer - President & CSO SELL $33.00 50,000 $1,650,000 562,596 -8.2%
2015-01-15 00:03 2015-01-12 Kauffman Michael Director, Officer - Chief Executive Officer SELL $33.00 50,000 $1,650,000 763,963 -6.1%
2015-01-15 00:06 2015-01-12 PAKIANATHAN DEEPIKA Director BUY $33.00 45,454 $1,499,982 21,883 +100.0%
2014-12-04 00:15 2014-12-01 Mirza Mansoor Raza Director OPT+S $43.52 10,000 $435,167 4,262 0.0%
2014-12-02 04:58 2014-11-26 Chione Ltd 10% owner SELL $41.92 278,115 $11,658,664 9,132,700 -3.0%
2014-11-26 05:13 2014-11-21 Chione Ltd 10% owner SELL $42.40 242,800 $10,294,040 9,410,815 -2.5%
2014-11-21 03:06 2014-11-18 Chione Ltd 10% owner SELL $40.09 65,968 $2,644,789 9,653,615 -0.7%
2014-11-13 04:10 2014-11-10 Chione Ltd 10% owner SELL $42.83 164,100 $7,028,026 9,586,883 -1.7%
SHOW ENTRIES

How to Interpret $KPTI Trades

Not every insider transaction in Karyopharm Therapeutics Inc. is a signal for immediate action. Professional investors look for "cluster buying"—when multiple executives simultaneously purchase $KPTI shares on the open market. It is crucial to distinguish between scheduled sales (under Rule 10b5-1) and voluntary increases in ownership, which demonstrate management’s true conviction that the stock is undervalued.

Data Source & Accuracy for KPTI

Insider activity data for Karyopharm Therapeutics Inc. is streamed in real-time directly from the SEC EDGAR system. We analyze raw Form 4 filings, filtering out technical adjustments and complex derivative transactions. This provides a transparent view of how ownership structure is evolving in $KPTI, allowing you to follow the capital of those with the most intimate knowledge of the company.

UNDERSTANDING THE DATA

FILING DATE: The date and time when the transaction was reported to the SEC. This is when the public first receives the information.

TRADE DATE: The actual day the insider executed the purchase or sale in the market.

INDUSTRY: The specific market sector the company operates in. Useful for identifying broader institutional capital flows across sectors.

OWNED AFTER: The total number of shares held by the insider following the transaction. This highlights the insider's remaining conviction in the company.

CHANGE %: The percentage increase or decrease of the insider's total position. Large percentage changes often carry more weight than the dollar amount alone.

TRADE TYPES DEFINITIONS

BUY: An open market purchase. Typically indicates an insider's belief that the stock is undervalued or poised for growth.

SELL: An open market sale. While often used for diversification or liquidity, large or unexpected sales can be a warning signal.

OPT+S (OPTION EXERCISE & SALE): This occurs when an insider exercises their stock options and sells them immediately. Often part of a structured compensation plan.