EcoR1 Capital, LLC
Director, 10% Owner | SEC CIK: 0001587114
Comprehensive Trading Performance Summary
The investment footprint of EcoR1 Capital, LLC as disclosed via official SEC Form 4 filings provides a critical window into professional capital allocation strategies. By tracking this specific portfolio, investors can analyze how this individual moves capital across different boards and sectors. High-conviction moves by key stakeholders often serve as leading indicators for future market performance, as they reflect the intimate operational knowledge and fiduciary confidence of those closest to the company's decision-making process. Monitoring these strategic accumulation or exit patterns helps bridge the gap between institutional boardrooms and the retail investment community.
| Filing Date | Trade Date | Ticker | Company Name | Industry | Relationship | Type | Price | Qty | Total, $ | Owned After | Change, % |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-01-13 04:28 | 2026-01-12 | AKTS | Aktis Oncology, Inc. | Pharmaceutical Preparations | Director | BUY | $18.00 | 2,222,222 | $39,999,996 | 347,305 | +100.0% |
| 2025-07-31 01:20 | 2025-07-28 | ADAP | Adaptimmune Therapeutics PLC | Biological Products, (No Diagnostic Substances) | 10% owner | SELL | $0.11 | 64,052,538 | $6,892,053 | 100,371,882 | -39.0% |
| 2025-05-20 01:35 | 2025-05-15 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $11.47 | 55,421 | $635,585 | 17,883,908 | +0.3% |
| 2025-05-17 01:52 | 2025-05-14 | ITOS | N/A | Other | 10% owner | BUY | $7.80 | 4,958,978 | $38,685,483 | 10,688,978 | +86.5% |
| 2025-05-07 02:06 | 2025-05-02 | PRTA | PROTHENA CORP PUBLIC LTD CO | Pharmaceutical Preparations | 10% owner | SELL | $8.10 | 6,279,684 | $50,839,694 | 5,304,596 | -54.2% |
| 2025-04-18 22:17 | 2025-04-16 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $11.32 | 128,713 | $1,456,413 | 17,828,487 | +0.7% |
| 2025-04-08 01:34 | 2025-04-03 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $11.42 | 317,208 | $3,623,975 | 17,699,774 | +1.8% |
| 2025-04-03 02:02 | 2025-03-31 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $11.75 | 127,415 | $1,497,317 | 17,382,566 | +0.7% |
| 2025-03-28 01:53 | 2025-03-25 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $12.61 | 97,349 | $1,227,308 | 17,255,151 | +0.6% |
| 2025-03-25 00:45 | 2025-03-20 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $12.92 | 127,198 | $1,643,246 | 17,157,802 | +0.7% |
| 2025-03-20 01:32 | 2025-03-17 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $12.55 | 228,463 | $2,866,548 | 17,030,604 | +1.4% |
| 2025-03-14 02:35 | 2025-03-11 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $12.13 | 1,081,980 | $13,120,955 | 16,802,141 | +6.9% |
| 2025-01-22 01:34 | 2025-01-16 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $13.88 | 141,429 | $1,963,544 | 15,720,161 | +0.9% |
| 2025-01-16 02:12 | 2025-01-13 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $13.59 | 167,654 | $2,278,803 | 15,578,732 | +1.1% |
| 2025-01-11 02:27 | 2025-01-08 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $13.21 | 225,119 | $2,974,813 | 15,411,078 | +1.5% |
| 2025-01-03 02:17 | 2024-12-30 | ANAB | ANAPTYSBIO, INC | Pharmaceutical Preparations | Director, 10% owner | BUY | $12.92 | 85,098 | $1,099,645 | 7,880,094 | +1.1% |
| 2025-01-03 01:51 | 2024-12-30 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $14.64 | 363,369 | $5,321,176 | 15,185,959 | +2.5% |
| 2024-12-28 02:41 | 2024-12-24 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $14.44 | 130,309 | $1,882,118 | 14,822,590 | +0.9% |
| 2024-12-26 20:46 | 2024-12-19 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $13.98 | 1,254,808 | $17,544,224 | 14,692,281 | +9.3% |
| 2024-11-09 03:24 | 2024-11-06 | TNGX | Tango Therapeutics, Inc. | Pharmaceutical Preparations | 10% owner | SELL | $3.12 | 2,700,000 | $8,435,610 | 10,630,736 | -20.3% |
| 2024-08-16 19:04 | 2024-08-14 | ANAB | ANAPTYSBIO, INC | Pharmaceutical Preparations | 10% owner | BUY | $36.50 | 273,972 | $9,999,978 | 7,794,996 | +3.6% |
| 2023-06-21 23:04 | 2023-06-16 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | 10% owner | BUY | $8.12 | 3,350,000 | $27,202,000 | 13,437,473 | +33.2% |
| 2023-03-31 00:47 | 2023-03-28 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | 10% owner | BUY | $8.00 | 200,000 | $1,600,000 | 10,087,473 | +2.0% |
| 2023-01-24 02:00 | 2023-01-19 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | 10% owner | BUY | $9.70 | 307,500 | $2,982,719 | 9,887,473 | +3.2% |
| 2023-01-19 02:27 | 2023-01-13 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | 10% owner | BUY | $9.84 | 985,100 | $9,697,521 | 9,579,973 | +11.5% |
| 2023-01-13 00:47 | 2023-01-10 | ZYME | Zymeworks Inc. | Pharmaceutical Preparations | 10% owner | BUY | $7.67 | 1,026,300 | $7,874,081 | 8,594,873 | +13.6% |
| 2023-01-12 02:26 | 2023-01-09 | VYGR | Voyager Therapeutics, Inc. | Biological Products, (No Diagnostic Substances) | 10% owner | SELL | $7.91 | 902,400 | $7,142,316 | 3,851,507 | -19.0% |
| 2022-06-24 00:21 | 2022-06-21 | VYGR | Voyager Therapeutics, Inc. | Biological Products, (No Diagnostic Substances) | 10% owner | BUY | $5.58 | 477,400 | $2,662,030 | 4,753,907 | +11.2% |
| 2022-05-09 13:04 | 2022-05-05 | ANAB | ANAPTYSBIO, INC | Pharmaceutical Preparations | 10% owner | SELL | $21.63 | 668,237 | $14,453,966 | 7,521,024 | -8.2% |
| 2022-05-09 13:04 | 2022-05-05 | ANAB | ANAPTYSBIO, INC | Pharmaceutical Preparations | 10% owner | BUY | $21.63 | 668,237 | $14,453,966 | 7,521,024 | +9.8% |
| 2022-05-09 13:01 | 2022-05-05 | PRTA | PROTHENA CORP PUBLIC LTD CO | Pharmaceutical Preparations | 10% owner | SELL | $29.02 | 1,062,736 | $30,840,599 | 11,584,280 | -8.4% |
| 2022-05-09 13:01 | 2022-05-05 | PRTA | PROTHENA CORP PUBLIC LTD CO | Pharmaceutical Preparations | 10% owner | BUY | $29.02 | 1,062,736 | $30,840,599 | 11,584,280 | +10.1% |
| 2022-01-13 02:12 | 2022-01-12 | PRTA | PROTHENA CORP PUBLIC LTD CO | Pharmaceutical Preparations | 10% owner | BUY | $37.50 | 300,000 | $11,250,300 | 11,584,280 | +2.7% |
| 2021-12-11 02:50 | 2021-12-01 | ODT | N/A | Other | 10% owner | SELL | $1.65 | 5,887,610 | $9,741,051 | 0 | -100.0% |
| 2021-12-11 02:50 | 2021-12-01 | ODT | N/A | Other | 10% owner | BUY | $1.66 | 185,941 | $308,662 | 5,701,669 | +3.4% |
| 2021-10-02 02:39 | 2021-09-30 | CRVS | Corvus Pharmaceuticals, Inc. | Pharmaceutical Preparations | 10% owner | SELL | $5.01 | 5,000,000 | $25,060,000 | 81,077 | -98.4% |
| 2021-05-04 23:51 | 2021-04-30 | ANAB | ANAPTYSBIO, INC | Pharmaceutical Preparations | Director, 10% owner | BUY | $23.24 | 221,500 | $5,147,439 | 7,520,424 | +3.0% |
| 2021-04-28 01:23 | 2021-04-23 | ANAB | ANAPTYSBIO, INC | Pharmaceutical Preparations | Director, 10% owner | BUY | $23.63 | 147,300 | $3,480,228 | 7,298,924 | +2.1% |
| 2021-03-25 18:14 | 2021-03-24 | PRTA | PROTHENA CORP PUBLIC LTD CO | Pharmaceutical Preparations | 10% owner | BUY | $20.75 | 875,000 | $18,156,250 | 11,034,280 | +8.6% |
| 2021-03-11 01:53 | 2021-03-08 | ANAB | ANAPTYSBIO, INC | Pharmaceutical Preparations | 10% owner | BUY | $18.93 | 3,308,800 | $62,622,680 | 7,151,624 | +86.1% |
| 2021-02-26 02:00 | 2021-02-23 | PRTA | PROTHENA CORP PUBLIC LTD CO | Pharmaceutical Preparations | 10% owner | BUY | $21.24 | 55,200 | $1,172,387 | 10,159,280 | +0.5% |
| 2021-02-26 01:58 | 2021-02-23 | ANAB | ANAPTYSBIO, INC | Pharmaceutical Preparations | 10% owner | BUY | $25.48 | 29,500 | $751,657 | 3,842,824 | +0.8% |
| 2021-02-23 23:57 | 2021-02-18 | PRTA | PROTHENA CORP PUBLIC LTD CO | Pharmaceutical Preparations | 10% owner | BUY | $23.65 | 44,100 | $1,043,075 | 10,104,080 | +0.4% |
| 2021-02-23 00:24 | 2021-02-18 | PRTA | PROTHENA CORP PUBLIC LTD CO | Pharmaceutical Preparations | 10% owner | BUY | $3.68 | 44,100 | $162,103 | 10,104,080 | +0.4% |
| 2021-02-18 03:14 | 2021-02-12 | PRTA | PROTHENA CORP PUBLIC LTD CO | Pharmaceutical Preparations | 10% owner | BUY | $21.56 | 633,340 | $13,657,280 | 10,059,980 | +6.7% |
| 2020-09-03 23:17 | 2020-09-01 | SURF | N/A | Other | 10% owner | SELL | $7.14 | 332,780 | $2,376,681 | 4,701,081 | -6.6% |
| 2020-07-03 00:20 | 2020-06-30 | AKUS | N/A | Other | 10% owner | BUY | $17.00 | 1,176,000 | $19,992,000 | 1,975,984 | +147.0% |
| 2014-03-29 02:11 | 2014-03-26 | GNVC | N/A | Other | 10% owner | BUY | $2.55 | 122,273 | $311,980 | 785,366 | +18.4% |
Tracking Multi-Role Insiders: EcoR1 Capital, LLC
High-level stakeholders like EcoR1 Capital, LLC, whether acting as directors, officers, or 10% owners, often possess unique cross-sector insights. Monitoring a specific CIK like 0001587114 allows investors to identify recurring patterns of trading success across various industries. When a large 10% shareholder or a key beneficial owner moves capital, it often signals a strategic shift in institutional or private conviction.
SEC Transparency for Key Stakeholders
Every market move made by EcoR1 Capital, LLC is a matter of public record under federal law. By aggregating Form 4 filings, we provide transparency into the portfolios of major players who hold significant influence. Following the money of those with a 10% stake or executive power helps bridge the information gap between the boardroom and the retail investor.
UNDERSTANDING THE DATA
FILING DATE: The date and time when the transaction was reported to the SEC. This is when the public first receives the information.
TRADE DATE: The actual day the insider executed the purchase or sale in the market.
INDUSTRY: The specific market sector the company operates in. Useful for identifying broader institutional capital flows across sectors.
OWNED AFTER: The total number of shares held by the insider following the transaction. This highlights the insider's remaining conviction in the company.
CHANGE %: The percentage increase or decrease of the insider's total position. Large percentage changes often carry more weight than the dollar amount alone.
TRADE TYPES DEFINITIONS
BUY: An open market purchase. Typically indicates an insider's belief that the stock is undervalued or poised for growth.
SELL: An open market sale. While often used for diversification or liquidity, large or unexpected sales can be a warning signal.
OPT+S (OPTION EXERCISE & SALE): This occurs when an insider exercises their stock options and sells them immediately. Often part of a structured compensation plan.