RA CAPITAL MANAGEMENT, L.P.
Director, 10% Owner, Other | SEC CIK: 0001346824
Comprehensive Trading Performance Summary
The investment footprint of RA CAPITAL MANAGEMENT, L.P. as disclosed via official SEC Form 4 filings provides a critical window into professional capital allocation strategies. By tracking this specific portfolio, investors can analyze how this individual moves capital across different boards and sectors. High-conviction moves by key stakeholders often serve as leading indicators for future market performance, as they reflect the intimate operational knowledge and fiduciary confidence of those closest to the company's decision-making process. Monitoring these strategic accumulation or exit patterns helps bridge the gap between institutional boardrooms and the retail investment community.
| Filing Date | Trade Date | Ticker | Company Name | Industry | Relationship | Type | Price | Qty | Total, $ | Owned After | Change, % |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-02-12 01:15 | 2026-02-09 | SGP | SpyGlass Pharma, Inc. | Surgical & Medical Instruments & Apparatus | Director, 10% owner | BUY | $16.00 | 3,690,000 | $59,040,000 | 2,054,678 | +100.0% |
| 2026-01-08 00:55 | 2026-01-05 | CLYM | Climb Bio, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $3.50 | 7,111 | $24,889 | 3,403,429 | +0.2% |
| 2025-12-16 03:55 | 2025-12-11 | CLYM | Climb Bio, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $2.40 | 314,561 | $754,726 | 3,396,318 | +10.2% |
| 2025-12-11 00:42 | 2025-12-08 | FULC | Fulcrum Therapeutics, Inc. | Pharmaceutical Preparations | 10% owner | SELL | $13.98 | 4,175,139 | $58,377,211 | 6,053,960 | -40.8% |
| 2025-11-25 01:43 | 2025-11-20 | SION | Sionna Therapeutics, Inc. | Pharmaceutical Preparations | Director, 10% owner | SELL | $39.61 | 30,316 | $1,200,705 | 159,033 | -16.0% |
| 2025-11-20 04:43 | 2025-11-17 | SION | Sionna Therapeutics, Inc. | Pharmaceutical Preparations | Director, 10% owner | SELL | $40.34 | 136,351 | $5,500,154 | 168,193 | -44.8% |
| 2025-11-15 02:14 | 2025-11-13 | WVE | Wave Life Sciences Ltd. | Pharmaceutical Preparations | Director, 10% owner | BUY | $6.69 | 1,000 | $6,688 | 18,203,009 | +0.0% |
| 2025-11-13 00:26 | 2025-11-07 | EVMN | Evommune, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $16.00 | 1,250,000 | $20,000,000 | 784,345 | +100.0% |
| 2025-10-31 01:40 | 2025-10-28 | VOR | Vor Biopharma Inc. | Biological Products, (No Diagnostic Substances) | Director, 10% owner | SELL | $25.90 | 400,408 | $10,368,926 | 779,652 | -33.9% |
| 2025-10-29 04:05 | 2025-10-24 | SION | Sionna Therapeutics, Inc. | Pharmaceutical Preparations | Director, 10% owner | SELL | $39.51 | 373,610 | $14,762,601 | 209,391 | -64.1% |
| 2025-10-28 03:04 | 2025-10-23 | VOR | Vor Biopharma Inc. | Biological Products, (No Diagnostic Substances) | Director, 10% owner | SELL | $28.06 | 221,166 | $6,204,856 | 1,180,060 | -15.8% |
| 2025-10-23 02:48 | 2025-10-20 | VOR | Vor Biopharma Inc. | Biological Products, (No Diagnostic Substances) | Director, 10% owner | SELL | $29.34 | 117,050 | $3,433,989 | 1,401,226 | -7.7% |
| 2025-10-18 01:03 | 2025-10-15 | VOR | Vor Biopharma Inc. | Biological Products, (No Diagnostic Substances) | Director, 10% owner | SELL | $29.54 | 464,025 | $13,707,345 | 15,104 | -96.8% |
| 2025-09-30 23:35 | 2025-09-26 | PEPG | PepGen Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $3.20 | 9,375,000 | $30,000,000 | 18,554,273 | +102.1% |
| 2025-09-09 00:59 | 2025-09-04 | MLYS | Mineralys Therapeutics, Inc. | Pharmaceutical Preparations | Director | BUY | $25.50 | 1,176,470 | $29,999,985 | 5,456,521 | +27.5% |
| 2025-06-30 23:56 | 2025-06-26 | CDTX | Cidara Therapeutics, Inc. | Biological Products, (No Diagnostic Substances) | Director, 10% owner | BUY | $44.00 | 2,272,727 | $99,999,988 | 3,365,523 | +208.0% |
| 2025-06-17 03:06 | 2025-06-12 | TYRA | Tyra Biosciences, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $10.19 | 163,287 | $1,664,695 | 10,259,291 | +1.6% |
| 2025-06-12 02:44 | 2025-06-09 | TYRA | Tyra Biosciences, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $10.19 | 186,850 | $1,904,002 | 10,096,004 | +1.9% |
| 2025-06-06 23:43 | 2025-06-04 | TYRA | Tyra Biosciences, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $9.70 | 1,211,198 | $11,751,285 | 9,909,154 | +13.9% |
| 2025-05-15 01:08 | 2025-05-12 | HOWL | Werewolf Therapeutics, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $0.91 | 536,426 | $487,182 | 6,237,482 | +9.4% |
| 2025-03-18 02:56 | 2025-03-13 | MLYS | Mineralys Therapeutics, Inc. | Pharmaceutical Preparations | Director | BUY | $13.50 | 1,296,296 | $17,499,996 | 4,280,051 | +43.4% |
| 2025-03-08 02:05 | 2025-03-05 | JANX | Janux Therapeutics, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $30.75 | 824,041 | $25,342,969 | 10,141,287 | +8.8% |
| 2025-02-11 01:04 | 2025-02-10 | SION | Sionna Therapeutics, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $18.00 | 1,125,000 | $20,250,000 | 2,324,498 | +93.8% |
| 2025-02-04 01:38 | 2025-01-30 | ETNB | N/A | Other | Director, 10% owner | BUY | $8.75 | 5,714,285 | $49,999,994 | 19,554,319 | +41.3% |
| 2024-11-14 01:00 | 2024-11-08 | TYRA | Tyra Biosciences, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $16.25 | 1,220,681 | $19,836,066 | 8,697,956 | +16.3% |
| 2024-10-31 01:12 | 2024-10-28 | SEPN | Septerna, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $18.00 | 4,170,000 | $75,060,000 | 1,471,943 | +100.0% |
| 2024-10-22 23:20 | 2024-10-18 | JANX | Janux Therapeutics, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $44.75 | 1,200,000 | $53,700,000 | 9,317,246 | +14.8% |
| 2024-09-19 01:02 | 2024-09-16 | BCAX | Bicara Therapeutics Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $18.00 | 1,833,000 | $32,994,000 | 2,652,575 | +223.7% |
| 2024-08-14 00:03 | 2024-08-09 | ANTX | AN2 Therapeutics, Inc. | Pharmaceutical Preparations | 10% owner | SELL | $1.08 | 3,525,094 | $3,807,102 | 300,853 | -92.1% |
| 2024-07-24 23:27 | 2024-07-22 | ARTV | Artiva Biotherapeutics, Inc. | Biological Products, (No Diagnostic Substances) | Director, 10% owner | BUY | $12.00 | 8,333,333 | $99,999,996 | 826,832 | +100.0% |
| 2024-07-02 04:29 | 2024-06-27 | ELYM | Climb Bio, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $3.84 | 13,008,546 | $49,952,817 | 2,866,375 | +100.0% |
| 2024-06-21 00:56 | 2024-06-17 | AVTE | Jade Biosciences, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $1.67 | 928,110 | $1,549,944 | 7,893,678 | +13.3% |
| 2024-04-04 23:15 | 2024-04-02 | BOLD | Boundless Bio, Inc. | Pharmaceutical Preparations | 10% owner | BUY | $16.00 | 312,500 | $5,000,000 | 295,844 | +100.0% |
| 2024-03-30 00:38 | 2024-03-27 | NKTX | Nkarta, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $10.00 | 3,000,000 | $30,000,000 | 10,050,818 | +42.5% |
| 2024-03-28 02:37 | 2024-03-25 | SPRY | ARS Pharmaceuticals, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $9.48 | 1,401,299 | $13,289,359 | 9,958,073 | +16.4% |
| 2024-03-26 03:48 | 2024-03-21 | LENZ | LENZ Therapeutics, Inc. | Biological Products, (No Diagnostic Substances) | Director, 10% owner | BUY | $15.03 | 998,009 | $15,000,075 | 694,755 | +100.0% |
| 2024-03-07 01:40 | 2024-03-04 | ETNB | N/A | Other | Director, 10% owner | BUY | $15.35 | 1,350,000 | $20,722,500 | 12,431,584 | +12.2% |
| 2024-02-14 00:33 | 2024-02-09 | PEPG | PepGen Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $10.64 | 2,557,593 | $27,212,790 | 9,179,273 | +38.6% |
| 2024-01-18 03:06 | 2023-12-11 | WVE | Wave Life Sciences Ltd. | Pharmaceutical Preparations | Director, 10% owner | BUY | $5.00 | 1,000,000 | $5,000,000 | 18,202,009 | +5.8% |
| 2024-01-13 01:01 | 2024-01-11 | SLDB | Solid Biosciences Inc. | Biological Products, (No Diagnostic Substances) | Director, 10% owner | BUY | $5.53 | 904,160 | $5,000,005 | 4,192,216 | +27.5% |
| 2023-12-14 00:33 | 2023-12-11 | WVE | Wave Life Sciences Ltd. | Pharmaceutical Preparations | Director, 10% owner | BUY | $5.00 | 1,000,000 | $5,000,000 | 19,202,009 | +5.5% |
| 2023-09-25 23:30 | 2023-09-21 | SPRY | ARS Pharmaceuticals, Inc. | Pharmaceutical Preparations | Director | BUY | $3.03 | 2,700,000 | $8,183,430 | 8,556,774 | +46.1% |
| 2023-09-01 00:26 | 2023-08-29 | SPRY | ARS Pharmaceuticals, Inc. | Pharmaceutical Preparations | Director | BUY | $6.20 | 3,750,000 | $23,250,000 | 5,856,774 | +178.0% |
| 2023-08-23 00:01 | 2023-08-18 | ANTX | AN2 Therapeutics, Inc. | Pharmaceutical Preparations | 10% owner | BUY | $9.00 | 1,777,778 | $16,000,002 | 5,135,683 | +52.9% |
| 2023-07-25 23:30 | 2023-07-21 | ABOS | Acumen Pharmaceuticals, Inc. | Biological Products, (No Diagnostic Substances) | Director, 10% owner | BUY | $7.75 | 5,161,290 | $39,999,998 | 13,043,179 | +65.5% |
| 2023-07-21 23:31 | 2023-07-19 | JANX | Janux Therapeutics, Inc. | Pharmaceutical Preparations | Director, 10% owner | BUY | $12.46 | 495,008 | $6,167,800 | 8,117,246 | +6.5% |
| 2023-07-07 23:30 | 2023-07-05 | BDTX | Black Diamond Therapeutics, Inc. | Biological Products, (No Diagnostic Substances) | Director | BUY | $5.00 | 935,850 | $4,679,250 | 3,213,828 | +41.1% |
| 2023-03-31 00:03 | 2023-03-28 | DICE | N/A | Other | Director, 10% owner | BUY | $29.07 | 509,145 | $14,798,707 | 7,070,205 | +7.8% |
| 2023-03-31 00:00 | 2023-03-24 | ETNB | N/A | Other | Director, 10% owner | BUY | $16.25 | 2,461,538 | $39,999,993 | 11,081,584 | +28.6% |
| 2023-03-28 00:01 | 2023-03-23 | DICE | N/A | Other | Director, 10% owner | BUY | $26.99 | 498,556 | $13,457,373 | 6,561,060 | +8.2% |
Tracking Multi-Role Insiders: RA CAPITAL MANAGEMENT, L.P.
High-level stakeholders like RA CAPITAL MANAGEMENT, L.P., whether acting as directors, officers, or 10% owners, often possess unique cross-sector insights. Monitoring a specific CIK like 0001346824 allows investors to identify recurring patterns of trading success across various industries. When a large 10% shareholder or a key beneficial owner moves capital, it often signals a strategic shift in institutional or private conviction.
SEC Transparency for Key Stakeholders
Every market move made by RA CAPITAL MANAGEMENT, L.P. is a matter of public record under federal law. By aggregating Form 4 filings, we provide transparency into the portfolios of major players who hold significant influence. Following the money of those with a 10% stake or executive power helps bridge the information gap between the boardroom and the retail investor.
UNDERSTANDING THE DATA
FILING DATE: The date and time when the transaction was reported to the SEC. This is when the public first receives the information.
TRADE DATE: The actual day the insider executed the purchase or sale in the market.
INDUSTRY: The specific market sector the company operates in. Useful for identifying broader institutional capital flows across sectors.
OWNED AFTER: The total number of shares held by the insider following the transaction. This highlights the insider's remaining conviction in the company.
CHANGE %: The percentage increase or decrease of the insider's total position. Large percentage changes often carry more weight than the dollar amount alone.
TRADE TYPES DEFINITIONS
BUY: An open market purchase. Typically indicates an insider's belief that the stock is undervalued or poised for growth.
SELL: An open market sale. While often used for diversification or liquidity, large or unexpected sales can be a warning signal.
OPT+S (OPTION EXERCISE & SALE): This occurs when an insider exercises their stock options and sells them immediately. Often part of a structured compensation plan.